Metagenics Bio Asorb PEA advanced

$84.50
Metagenics is a practitioner-only brand. As a requirement from Metagenics, to purchase products from the Metagenics range, please sign into your mammoth account or sign-up and complete the health questionnaire. One of our health care practitioners will review this information in order to provide you with access to the product.
Once you're signed in and make a purchase, your credit card details and order will be taken however you will not be charged until our health care practitioner has conducted this review.

Bio Absorb PEA Advanced is a powerful, science-backed formula developed for the relief of mild nerve pain, including neuralgia, sciatica, and compression neuropathy. It features Palmitoylethanolamide (PEA) delivered via the Levagen+™ (LipiSperse®) delivery system for optimal absorption, combined with affron® (standardized saffron extract) and vitamin B1.

This advanced formulation targets multiple pain pathways to help break the pain cycle, modulate pain amplification, and enhance endocannabinoid system activity—offering a non-drug approach to chronic nerve pain.


CLINICAL BENEFITS

  • Relieves neuropathic pain, including sciatica, neuralgia, and compression neuropathies

  • Neuroprotective, anti-inflammatory, and analgesic effects

  • Modulates endocannabinoid activity via PPAR-α activation

  • Downregulates microglial and mast cell activity to reduce central sensitisation

  • Desensitises pain receptors TRPA1 and TRPV1, reducing hyperalgesia

  • Supports healthy nerve function and reduces excitability with vitamin B1


HOW IT WORKS

  • PEA (Palmitoylethanolamide) activates PPAR-α, impacting the endocannabinoid system and reducing inflammatory signalling

  • TRPV1 and TRPA1 receptors, linked to nerve pain and hypersensitivity, are desensitised by PEA and saffron (safranal) respectively

  • Vitamin B1 addresses potential deficiency-related neuropathy and reduces dorsal root ganglion excitability, a key factor in central pain amplification


DELIVERY TECHNOLOGY

  • Uses Levagen+™ (LipiSperse®) for significantly enhanced PEA bioavailability

  • Contains affron®, a clinically studied saffron extract for mood and pain support

  • Includes Vitamin B1 for additional nerve health benefits


DID YOU KNOW?

  • 1 in 5 people with chronic pain suffer from neuropathic pain

  • Many patients do not respond adequately to conventional treatments due to opioid-induced hyperalgesia

  • PEA and saffron have demonstrated synergistic effects and are safe for concurrent use with standard pain medications

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