Metagenics Bio Asorb PEA advanced
Bio Absorb PEA Advanced is a powerful, science-backed formula developed for the relief of mild nerve pain, including neuralgia, sciatica, and compression neuropathy. It features Palmitoylethanolamide (PEA) delivered via the Levagen+™ (LipiSperse®) delivery system for optimal absorption, combined with affron® (standardized saffron extract) and vitamin B1.
This advanced formulation targets multiple pain pathways to help break the pain cycle, modulate pain amplification, and enhance endocannabinoid system activity—offering a non-drug approach to chronic nerve pain.
CLINICAL BENEFITS
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Relieves neuropathic pain, including sciatica, neuralgia, and compression neuropathies
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Neuroprotective, anti-inflammatory, and analgesic effects
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Modulates endocannabinoid activity via PPAR-α activation
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Downregulates microglial and mast cell activity to reduce central sensitisation
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Desensitises pain receptors TRPA1 and TRPV1, reducing hyperalgesia
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Supports healthy nerve function and reduces excitability with vitamin B1
HOW IT WORKS
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PEA (Palmitoylethanolamide) activates PPAR-α, impacting the endocannabinoid system and reducing inflammatory signalling
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TRPV1 and TRPA1 receptors, linked to nerve pain and hypersensitivity, are desensitised by PEA and saffron (safranal) respectively
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Vitamin B1 addresses potential deficiency-related neuropathy and reduces dorsal root ganglion excitability, a key factor in central pain amplification
DELIVERY TECHNOLOGY
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Uses Levagen+™ (LipiSperse®) for significantly enhanced PEA bioavailability
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Contains affron®, a clinically studied saffron extract for mood and pain support
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Includes Vitamin B1 for additional nerve health benefits
DID YOU KNOW?
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1 in 5 people with chronic pain suffer from neuropathic pain
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Many patients do not respond adequately to conventional treatments due to opioid-induced hyperalgesia
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PEA and saffron have demonstrated synergistic effects and are safe for concurrent use with standard pain medications
